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Colon - Gents

Rates per 100,000 inhabitants

Table 1: Incidence: frequencies, crude and standardized rates per year

Incidence		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		388	400	455	421	422	441	427	489	3443
Crude rate		65.0	67.5	77.1	72.0	72.6	73.9	69.6	79.0	72.1 (69.7‑74.6)
Standardized rate	Italy 2001	69.4	69.8	78.2	72.7	70.7	72.2	69.3	78.2	72.5 (70.1‑75.0)
Standardized rate	Europe	44.0	44.7	50.7	45.7	46.5	45.6	44.0	50.3	46.4 (44.8‑48.0)
Standardized rate	World	28.7	29.4	33.4	29.6	30.7	29.7	28.8	32.8	30.3 (29.3‑31.4)

Table 2: Mortality: frequencies, crude and standardized rates per year

Mortality		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		203	164	203	202	169	201	198	193	1533
Crude rate		34.0	27.7	34.4	34.5	29.1	33.7	32.3	31.2	32.1 (30.5‑33.8)
Standardized rate	Italy 2001	37.8	29.6	36.3	35.9	29.6	34.3	34.3	32.5	33.7 (32.0‑35.5)
Standardized rate	Europe	22.4	18.1	21.9	21.6	17.8	20.3	20.4	18.9	20.1 (19.1‑21.2)
Standardized rate	World	14.0	11.5	13.6	13.6	11.3	12.6	12.6	11.6	12.6 (11.9‑13.3)

Table 3: Register quality indicators per year

Indicator	1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Mortality/Incidence ratio (%)	54.5	42.4	46.4	49.4	41.9	47.5	49.5	41.6	46.5
Cito-histologically confirmed (%)	89.2	90.5	93.0	95.7	95.0	94.6	96.3	95.7	93.9
Death certificate only - DCO (%)	2.1	1.5	0.2	0.7	0.7	1.6	0.7	0.8	1.0

Table 4: Comparison of Italian Registries mean prevalence by macro-areas

Graf 04

_	Milan	North West	North East	Centre	South	Italy
Incidence	46.6	44.6	47.1	43.8	30.4	43.3
Mortality	19.3	20.1	18.5	17.8	15.6	18.1

Table 5: Basis of diagnosis per period

_	1999‑2002	%	2003‑2006	%	1999‑2006	%
Histological	1530	91.9	1697	95.4	3227	93.7
Citological	4	0.2	0	0.0	4	0.1
Clinical	111	6.7	62	3.5	173	5.0
DCO	18	1.1	17	1.0	35	1.0

Table 6: More frequent morphologies

Morphology	N	%
Adenocarcinoma, NOS	1332	78.5
Mucinous adenocarcinoma	148	8.7
Adenocarcinoma in tubulovillous adenoma	95	5.6
Adenocarcinoma, intestinal type (C16._)	22	1.3
Adenocarcinoma in villous adenoma	21	1.2
Adenocarcinoma in adenomatous polyp	18	1.1

Table 7: Age distribution of rates

Graf 07

Age groups	Incidence	Mortality
0	0.0	0.0
1-4	0.0	0.0
5-9	0.0	0.0
10-14	0.0	0.0
15-19	0.0	0.0
20-24	0.0	0.0
25-29	1.2	0.6
30-34	2.2	0.9
35-39	5.6	0.4
40-44	10.5	3.5
45-49	12.8	8.6
50-54	40.1	14.3
55-59	71.0	17.6
60-64	120.6	33.2
65-69	187.9	62.2
70-74	271.0	95.0
75-79	348.7	164.7
80-84	442.3	251.0
85+	416.1	348.7

Table 8: Temporal trends of rates

Graf 08

Year	Mortality	Incidence
1999	22.4	44.0
2000	18.1	44.7
2001	21.9	50.7
2002	21.6	45.7
2003	17.8	46.5
2004	20.3	45.6
2005	20.4	44.0
2006	18.9	50.3

Table 10: Comparison of Italian Registries mean prevalence by macro-areas

Graf 10

Years since diagnosis	Italy	South	Centre	North East	North West	Milan
0-2	97.6	57.5	103.6	105.2	109.5	107.3
2-5	97.4	56.4	99.7	108.1	107.5	117.2
5-10	99.5	51.8	118.3	103.0	110.2	108.0
10-15	57.5	25.7	62.9	68.9	62.9	57.8
15-20	27.1	12.7	31.1	28.8	32.2	29.3
>20	23.2	12.1	26.0	25.0	26.0	25.9

Table 11: 5 years relative survival by macro-areas

Graf 11

Area	Relative survival (95% CI)
Milan	61.0 (58.3‑63.8)
North West	57.9 (56.5‑59.3)
North Est	60.3 (59.1‑61.4)
Centre	59.9 (58.0‑61.8)
South	57.9 (55.6‑60.2)
Italy	59.3 (58.5‑60.0)

Table 12: Relative survival by age since diagnosis

Age class	0	1	2	3	4	5
15-44	100.00	83.70	75.30	68.00	65.10	65.10
45-59	100.00	84.60	78.10	72.70	67.80	66.40
60-74	100.00	83.80	76.20	70.40	66.60	65.00
75+	100.00	72.60	64.80	59.10	55.20	52.90

Table 13: 5 years relative survival by biennium of incidence

Years since diagnosis	1999‑2000	2001‑2002	2003‑2004	2005‑2006
1	75.9	77.9	80.5	82.6
2	67.2	70.8	72.3	75.8
3	59.1	65.3	68.1	70.3
4	54.7	61.5	64.2	66.1
5	53.1	59.7	61.5	64.8

Table 14: Rates distribution by deprivation index

‑	1	2	3	4	5
Incidence	68.1	66.8	75	72.3	68.4
Mortality	24.9	26.9	27	35.5	35.9

Table 15: Relative survival by deprivation index

Years since diagnosis	Most deprived	Most affluent
0	100.0	100.0
1	78.0	83.5
2	70.1	75.9
3	64.9	72.2
4	61.1	67.5
5	56.9	63.9