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Kidney and urinary tract - Gents

Rates per 100,000 inhabitants

Table 1: Incidence: frequencies, crude and standardized rates per year

Incidence		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		167	185	195	191	183	193	187	180	1481
Crude rate		28.0	31.2	33.1	32.7	31.5	32.3	30.5	29.1	31.0 (29.5‑32.6)
Standardized rate	Italy 2001	27.4	29.9	32.9	31.5	29.6	31.5	30.2	28.4	30.2 (28.7‑31.8)
Standardized rate	Europe	20.6	21.9	23.5	23.3	21.0	21.5	20.5	19.7	21.5 (20.4‑22.7)
Standardized rate	World	14.7	15.6	16.2	16.8	15.1	14.9	13.8	13.4	15.0 (14.2‑15.9)

Table 2: Mortality: frequencies, crude and standardized rates per year

Mortality		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		70	61	53	63	66	68	75	62	518
Crude rate		11.7	10.3	9.0	10.8	11.3	11.4	12.2	10.0	10.9 (9.9‑11.8)
Standardized rate	Italy 2001	12.3	10.7	9.3	11.0	10.7	11.1	11.6	9.9	10.9 (9.9‑11.8)
Standardized rate	Europe	7.6	7.3	5.9	7.0	6.8	7.0	7.1	6.1	6.9 (6.3‑7.5)
Standardized rate	World	5.0	5.2	3.8	4.5	4.5	4.5	4.6	4.0	4.5 (4.1‑5.0)

Table 3: Register quality indicators per year

Indicator	1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Mortality/Incidence ratio (%)	44.9	35.8	28.3	34.9	36.1	35.2	38.4	34.9	36.1
Cito-histologically confirmed (%)	89.8	86.5	83.6	91.1	88.0	86.0	84.5	87.8	87.1
Death certificate only - DCO (%)	0.6	1.1	1.5	0.5	1.1	0.5	2.1	0.6	1.0

Table 4: Comparison of Italian Registries mean prevalence by macro-areas

Graf 04

_	Milan	North West	North East	Centre	South	Italy
Incidence	20.6	20.5	20.9	22.4	11.9	19.7
Mortality	6.8	6.6	7.5	6.3	4.2	6.6

Table 5: Basis of diagnosis per period

_	1999‑2002	%	2003‑2006	%	1999‑2006	%
Histological	616	83.5	624	84.0	1240	83.7
Citological	31	4.2	19	2.6	50	3.4
Clinical	84	11.4	91	12.3	175	11.8
DCO	7	1.0	8	1.1	15	1.0

Table 6: More frequent morphologies

Morphology	N	%
Renal cell carcinoma, NOS (C64.9)	269	41.8
Clear cell adenocarcinoma, NOS	161	25.0
Papillary transitional cell carcinoma (C67._)	59	9.2
Transitional cell carcinoma, NOS	56	8.7
Papillary carcinoma, NOS	22	3.4
Renal cell carcinoma, chromophobe type (C64.9)	20	3.1

Table 7: Age distribution of rates

Graf 07

Age groups	Incidence	Mortality
0	0.0	0.0
1-4	3.3	0.0
5-9	1.0	0.0
10-14	0.0	0.0
15-19	0.0	0.0
20-24	0.0	0.0
25-29	0.6	0.0
30-34	1.8	0.4
35-39	3.5	0.4
40-44	9.5	0.0
45-49	11.0	1.8
50-54	28.5	4.1
55-59	31.4	7.5
60-64	53.6	17.2
65-69	76.1	30.4
70-74	132.0	47.1
75-79	128.3	56.7
80-84	126.4	83.7
85+	105.5	38.1

Table 8: Temporal trends of rates

Graf 08

Year	Mortality	Incidence
1999	7.6	20.6
2000	7.3	21.9
2001	5.9	23.5
2002	7.0	23.3
2003	6.8	21.0
2004	7.0	21.5
2005	7.1	20.5
2006	6.1	19.7

Table 10: Comparison of Italian Registries mean prevalence by macro-areas

Graf 10

Years since diagnosis	Italy	South	Centre	North East	North West	Milan
0-2	41.0	22.0	46.0	45.4	44.0	46.8
2-5	47.4	21.0	50.9	52.7	55.2	57.6
5-10	53.3	22.7	63.0	56.1	61.0	66.1
10-15	34.1	13.4	38.0	42.2	36.0	37.6
15-20	17.4	7.5	19.3	19.9	19.1	21.1
>20	19.6	8.7	22.2	22.1	21.3	23.7

Table 11: 5 years relative survival by macro-areas

Graf 11

Area	Relative survival (95% CI)
Milan	65.3 (61.5‑69.0)
North West	62.1 (57.3‑66.6)
North Est	62.4 (58.4‑66.2)
Centre	64.2 (55.8‑71.4)
South	57.9 (47.9‑66.6)
Italy	62.1 (59.3‑64.7)

Table 12: Relative survival by age since diagnosis

Age class	0	1	2	3	4	5
15-44	100.00	91.00	89.50	89.50	88.10	88.10
45-59	100.00	91.40	86.70	85.10	81.90	80.40
60-74	100.00	81.50	76.30	72.20	68.40	66.80
75+	100.00	70.30	61.60	56.60	53.50	51.30

Table 13: 5 years relative survival by biennium of incidence

Years since diagnosis	1999‑2000	2001‑2002	2003‑2004	2005‑2006
1	78.7	80.8	80.9	83.5
2	74.5	75.5	72.4	78.2
3	72.3	71.8	68.2	73.9
4	68.5	69.5	64.9	68.9
5	66.6	68.9	63	66.9

Table 14: Rates distribution by deprivation index

‑	1	2	3	4	5
Incidence	27.2	29	30.6	28.7	29.9
Mortality	8.1	10.8	12.7	8.9	12.9

Table 15: Relative survival by deprivation index

Years since diagnosis	Most deprived	Most affluent
0	100.0	100.0
1	79.4	86.3
2	77.2	77.2
3	71.8	73.9
4	65.1	67.2
5	64.0	63.6