Brain and central nervous system - GentsRates per 100,000 inhabitants
Table 1: Incidence: frequencies, crude and standardized rates per year
Incidence | 1999 | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 1999‑2006 |
---|
Count | 72 | 48 | 74 | 77 | 66 | 72 | 56 | 68 | 533 |
---|
Crude rate | 12.1 | 8.1 | 12.5 | 13.2 | 11.3 | 12.1 | 9.1 | 11.0 | 11.2 (10.2‑12.2) |
---|
Standardized rate | Italy 2001 | 11.8 | 7.9 | 12.3 | 12.9 | 11.0 | 11.3 | 8.9 | 10.8 | 10.8 (9.9‑11.8) |
---|
Standardized rate | Europe | 10.1 | 6.2 | 9.5 | 9.9 | 8.9 | 8.4 | 7.3 | 8.9 | 8.6 (7.8‑9.4) |
---|
Standardized rate | World | 8.5 | 4.9 | 7.4 | 7.8 | 7.4 | 6.4 | 5.8 | 7.4 | 6.9 (6.2‑7.7) |
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Table 2: Mortality: frequencies, crude and standardized rates per year
Mortality | 1999 | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 1999‑2006 |
---|
Count | 58 | 37 | 48 | 46 | 41 | 44 | 38 | 37 | 349 |
---|
Crude rate | 9.7 | 6.2 | 8.1 | 7.9 | 7.0 | 7.4 | 6.2 | 6.0 | 7.3 (6.6‑8.1) |
---|
Standardized rate | Italy 2001 | 9.5 | 6.0 | 7.9 | 7.4 | 6.4 | 6.8 | 5.8 | 5.8 | 7.0 (6.2‑7.7) |
---|
Standardized rate | Europe | 7.2 | 4.4 | 6.4 | 5.4 | 5.1 | 4.9 | 4.1 | 4.2 | 5.2 (4.7‑5.8) |
---|
Standardized rate | World | 5.2 | 3.0 | 4.7 | 3.9 | 3.9 | 3.6 | 3.0 | 3.0 | 3.8 (3.3‑4.3) |
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Table 3: Register quality indicators per year
Indicator | 1999 | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 1999‑2006 |
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Mortality/Incidence ratio (%) | 80.5 | 75.9 | 64.2 | 57.4 | 58.2 | 60.2 | 65.2 | 53.7 | 64.8 |
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Cito-histologically confirmed (%) | 54.2 | 52.1 | 63.5 | 66.2 | 63.6 | 65.3 | 76.8 | 69.1 | 64.0 |
---|
Death certificate only - DCO (%) | 0.0 | 2.1 | 0.0 | 2.6 | 3.0 | 4.2 | 0.0 | 0.0 | 1.5 |
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Table 4: Comparison of Italian Registries mean prevalence by macro-areas
_ | Milan | North West | North East | Centre | South | Italy |
---|
Incidence | 8.3 | 8.3 | 8.7 | 9.4 | 8.2 | 8.8 |
---|
Mortality | 4.6 | 5.0 | 5.9 | 6.8 | 6.7 | 6.0 |
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Table 5: Basis of diagnosis per period
_ | 1999‑2002 | % | 2003‑2006 | % | 1999‑2006 | % |
---|
Histological | 162 | 59.8 | 179 | 68.3 | 341 | 64.0 |
---|
Citological | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
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Clinical | 106 | 39.1 | 78 | 29.8 | 184 | 34.5 |
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DCO | 3 | 1.1 | 5 | 1.9 | 8 | 1.5 |
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Table 6: More frequent morphologies
Morphology | N | % |
---|
Glioblastoma, NOS (C71._) | 98 | 54.7 |
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Astrocytoma, anaplastic (C71._) | 19 | 10.6 |
---|
Astrocytoma, NOS (C71._) | 10 | 5.6 |
---|
Glioma, malignant (C71._) | 9 | 5.0 |
---|
Oligodendroglioma, NOS (C71._) | 7 | 3.9 |
---|
Mixed glioma (C71._) | 6 | 3.4 |
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Table 7: Age distribution of rates
Age groups | Incidence | Mortality |
---|
0 | 0.0 | 0.0 |
---|
1-4 | 4.4 | 0.0 |
---|
5-9 | 4.1 | 1.0 |
---|
10-14 | 3.2 | 0.0 |
---|
15-19 | 1.1 | 0.0 |
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20-24 | 2.8 | 0.9 |
---|
25-29 | 3.7 | 2.5 |
---|
30-34 | 2.7 | 0.9 |
---|
35-39 | 3.9 | 0.9 |
---|
40-44 | 4.5 | 3.5 |
---|
45-49 | 6.7 | 3.1 |
---|
50-54 | 11.6 | 4.8 |
---|
55-59 | 12.6 | 8.2 |
---|
60-64 | 17.2 | 8.9 |
---|
65-69 | 33.7 | 23.8 |
---|
70-74 | 25.1 | 23.6 |
---|
75-79 | 37.4 | 27.8 |
---|
80-84 | 32.4 | 18.8 |
---|
85+ | 14.7 | 2.9 |
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Table 8: Temporal trends of rates
Year | Mortality | Incidence |
---|
1999 | 7.2 | 10.1 |
---|
2000 | 4.4 | 6.2 |
---|
2001 | 6.4 | 9.5 |
---|
2002 | 5.4 | 9.9 |
---|
2003 | 5.1 | 8.9 |
---|
2004 | 4.9 | 8.4 |
---|
2005 | 4.1 | 7.3 |
---|
2006 | 4.2 | 8.9 |
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Table 10: Comparison of Italian Registries mean prevalence by macro-areas
Years since diagnosis | Italy | South | Centre | North East | North West | Milan |
---|
0-2 | 10.4 | 8.4 | 11.8 | 11.4 | 9.2 | 10.4 |
---|
2-5 | 6.1 | 5.4 | 7.6 | 5.5 | 6.6 | 6.8 |
---|
5-10 | 7.2 | 8.9 | 8.3 | 6.5 | 6.8 | 6.6 |
---|
10-15 | 4.4 | 5.1 | 4.4 | 3.9 | 4.4 | 4.8 |
---|
15-20 | 3.9 | 4.1 | 4.5 | 3.7 | 3.7 | 4.2 |
---|
>20 | 18.9 | 17.1 | 21.3 | 18.4 | 19.5 | 19.8 |
---|
Table 11: 5 years relative survival by macro-areas
Area | Relative survival (95% CI) |
---|
Milan | 23.4 (17.8‑28.9) |
---|
North West | 22.2 (19.7‑24.8) |
---|
North Est | 19.9 (17.8‑22.1) |
---|
Centre | 23.7 (20.3‑27.3) |
---|
South | 20.4 (17.3‑23.6) |
---|
Italy | 21.2 (19.9‑22.6) |
---|
Table 12: Relative survival by age since diagnosis
Age class | 0 | 1 | 2 | 3 | 4 | 5 |
---|
15-44 | 100.00 | 85.70 | 73.70 | 64.20 | 58.50 | 51.10 |
---|
45-59 | 100.00 | 57.30 | 39.10 | 23.80 | 20.60 | 16.10 |
---|
60-74 | 100.00 | 31.20 | 14.90 | 10.60 | 8.10 | 7.10 |
---|
75+ | 100.00 | 12.10 | 8.30 | 7.80 | 7.20 | 7.20 |
---|
Table 13: 5 years relative survival by biennium of incidence
Years since diagnosis | 1999‑2000 | 2001‑2002 | 2003‑2004 | 2005‑2006 |
---|
1 | 40.9 | 38.2 | 48.8 | 43.2 |
---|
2 | 26.9 | 25.4 | 35.6 | 31.5 |
---|
3 | 20.7 | 22.3 | 25.3 | 25.6 |
---|
4 | 19.8 | 19.4 | 23.1 | 21.2 |
---|
5 | 17.1 | 16.2 | 22.3 | 18.5 |
---|
Table 14: Rates distribution by deprivation index
‑ | 1 | 2 | 3 | 4 | 5 |
---|
Incidence | 9.3 | 8.6 | 11.6 | 11.5 | 11.7 |
---|
Mortality | 6.1 | 6.2 | 5 | 7.6 | 6.6 |
---|
Table 15: Relative survival by deprivation index
Years since diagnosis | Most deprived | Most affluent |
---|
0 | 100.0 | 100.0 |
---|
1 | 46.0 | 43.7 |
---|
2 | 31.4 | 29.6 |
---|
3 | 29.6 | 23.8 |
---|
4 | 24.2 | 23.8 |
---|
5 | 22.5 | 22.4 |
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