Elenco delle sezioni principali del sito:

PdfLiver - Ladies

Rates per 100,000 inhabitants

Table 1: Incidence: frequencies, crude and standardized rates per year

Incidence199920002001200220032004200520061999‑2006
Count979611591111108111101830
Crude rate14.314.217.113.616.716.016.214.615.3 (14.3‑16.4)
Standardized rateItaly 200110.810.212.39.711.611.211.110.310.9 (10.2‑11.7)
Standardized rateEurope6.86.37.46.17.06.86.76.36.7 (6.2‑7.2)
Standardized rateWorld4.74.04.74.04.44.34.34.24.3 (4.0‑4.7)

Table 2: Mortality: frequencies, crude and standardized rates per year

Mortality199920002001200220032004200520061999‑2006
Count116101105100100859290789
Crude rate17.114.915.615.015.012.613.413.014.6 (13.6‑15.6)
Standardized rateItaly 200112.410.811.010.410.48.68.88.810.2 (9.5‑10.9)
Standardized rateEurope7.16.66.36.26.35.05.05.36.0 (5.5‑6.5)
Standardized rateWorld4.44.13.94.04.03.13.13.23.7 (3.4‑4.1)

Table 3: Register quality indicators per year

Indicator199920002001200220032004200520061999‑2006
Mortality/Incidence ratio (%)114.8105.989.4107.289.776.879.385.493.6
Cito-histologically confirmed (%)36.136.538.344.034.238.936.039.637.8
Death certificate only - DCO (%)5.27.36.111.08.14.67.28.97.2

Table 4: Comparison of Italian Registries mean prevalence by macro-areas

Graf 04
_MilanNorth WestNorth EastCentreSouthItaly
Incidence6.75.86.34.79.16.3
Mortality5.45.04.84.77.45.2

Table 5: Basis of diagnosis per period

_1999‑2002%2003‑2006%1999‑2006%
Histological13132.814132.727232.8
Citological235.8194.4425.1
Clinical21654.123855.245454.7
DCO297.3317.2607.2

Table 6: More frequent morphologies

MorphologyN%
Hepatocellular carcinoma, NOS (C22.0)9660.0
Cholangiocarcinoma (C22.1, C24.0)2012.5
Hepatocellular carcinoma, fibrolamellar (C22.0)159.4
Adenocarcinoma, NOS127.5
Carcinoma, NOS63.8
Hepatocellular carcinoma, clear cell type (C22.0)31.9

Table 7: Age distribution of rates

Graf 07
Age groupsIncidenceMortality
04.30.0
1-40.00.0
5-90.00.0
10-140.00.0
15-190.00.0
20-240.00.0
25-290.00.0
30-340.00.0
35-390.50.0
40-441.50.0
45-492.31.2
50-542.43.0
55-595.35.8
60-6412.011.5
65-6925.515.6
70-7449.035.9
75-7975.058.4
80-8473.675.3
85+51.658.6

Table 8: Temporal trends of rates

Graf 08
YearMortalityIncidence
19997.16.8
20006.66.3
20016.37.4
20026.26.1
20036.37.0
20045.06.8
20055.06.7
20065.36.3

Table 10: Comparison of Italian Registries mean prevalence by macro-areas

Graf 10
Years since diagnosisItalySouthCentreNorth EastNorth WestMilan
0-210.510.76.810.612.415.4
2-55.66.04.35.36.89.2
5-102.63.72.91.34.25.2
10-151.81.31.02.41.41.8
15-200.50.80.30.30.60.5
>200.81.10.60.70.71.1

Table 11: 5 years relative survival by macro-areas

Graf 11
AreaRelative survival (95% CI)
Milan19.7 (15.7‑23.7)
North West17.6 (15.0‑20.4)
North Est15.3 (12.8‑18.0)
Centre17.4 (13.0‑22.4)
South13.6 (10.8‑16.7)
Italy16.0 (14.5‑17.5)

Table 12: Relative survival by age since diagnosis

Age class012345
15-44100.0046.3034.2029.4024.6024.60
45-59100.0055.3045.1033.6025.6019.50
60-74100.0040.4028.8020.4015.2011.80

Table 13: 5 years relative survival by biennium of incidence

Years since diagnosis1999‑20002001‑20022003‑20042005‑2006
145.844.85046.5
23230.841.437.8
321.523.532.427
417.515.223.623.1
513.91119.717.7

Table 14: Rates distribution by deprivation index

12345
Incidence13.214.315.116.717.2
Mortality121114.71314.5

Table 15: Relative survival by deprivation index

Years since diagnosisMost deprivedMost affluent
0100.0100.0
145.351.7
235.240.6
325.832.2
419.425.2
515.016.2