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Skin melanoma - Gents

Rates per 100,000 inhabitants

Table 1: Incidence: frequencies, crude and standardized rates per year

Incidence		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		94	107	135	136	97	130	118	100	917
Crude rate		15.8	18.1	22.9	23.3	16.7	21.8	19.2	16.2	19.2 (18.0‑20.5)
Standardized rate	Italy 2001	15.5	17.3	22.4	22.4	15.7	20.6	18.4	16.1	18.5 (17.3‑19.8)
Standardized rate	Europe	12.4	13.6	17.1	17.6	12.5	15.5	14.2	12.1	14.3 (13.4‑15.3)
Standardized rate	World	9.4	10.2	12.8	13.4	9.5	11.6	10.2	8.8	10.7 (9.9‑11.5)

Table 2: Mortality: frequencies, crude and standardized rates per year

Mortality		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		30	34	25	21	25	32	30	32	229
Crude rate		5.0	5.7	4.2	3.6	4.3	5.4	4.9	5.2	4.8 (4.2‑5.5)
Standardized rate	Italy 2001	5.0	5.9	4.5	3.2	4.3	5.2	4.8	5.3	4.8 (4.2‑5.5)
Standardized rate	Europe	3.7	3.9	2.8	2.6	2.8	3.9	3.2	3.8	3.3 (2.9‑3.8)
Standardized rate	World	2.6	2.5	1.9	2.0	1.9	2.7	2.2	2.7	2.3 (2.0‑2.7)

Table 3: Register quality indicators per year

Indicator	1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Mortality/Incidence ratio (%)	32.3	34.1	20.1	14.3	27.4	25.2	26.1	32.9	25.9
Cito-histologically confirmed (%)	100.0	98.1	100.0	100.0	100.0	100.0	100.0	100.0	99.8
Death certificate only - DCO (%)	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0

Table 4: Comparison of Italian Registries mean prevalence by macro-areas

Graf 04

_	Milan	North West	North East	Centre	South	Italy
Incidence	13.6	12.6	12.6	11.9	6.9	11.4
Mortality	3.4	2.8	3.0	2.5	2.1	2.7

Table 5: Basis of diagnosis per period

_	1999‑2002	%	2003‑2006	%	1999‑2006	%
Histological	470	99.6	445	100.0	915	99.8
Citological	0	0.0	0	0.0	0	0.0
Clinical	2	0.4	0	0.0	2	0.2
DCO	0	0.0	0	0.0	0	0.0

Table 6: More frequent morphologies

Morphology	N	%
Superficial spreading melanoma (C44._)	178	40.0
Epithelioid cell melanoma	121	27.2
Malignant melanoma, NOS (except juvenile melanoma M87700)	61	13.7
Nodular melanoma (C44._)	31	7.0
Mixed epithelioid and spindle cell melanoma	23	5.2
Lentigo maligna melanoma (C44._)	18	4.0

Table 7: Age distribution of rates

Graf 07

Age groups	Incidence	Mortality
0	0.0	0.0
1-4	0.0	0.0
5-9	0.0	0.0
10-14	1.1	0.0
15-19	3.4	0.0
20-24	1.9	0.0
25-29	3.1	0.6
30-34	9.4	0.9
35-39	8.2	2.2
40-44	10.5	1.0
45-49	12.2	1.2
50-54	19.0	4.8
55-59	30.8	7.5
60-64	32.6	12.1
65-69	46.3	9.9
70-74	38.5	11.8
75-79	63.1	17.1
80-84	52.9	18.8
85+	46.9	35.2

Table 8: Temporal trends of rates

Graf 08

Year	Mortality	Incidence
1999	3.7	12.4
2000	3.9	13.6
2001	2.8	17.1
2002	2.6	17.6
2003	2.8	12.5
2004	3.9	15.5
2005	3.2	14.2
2006	3.8	12.1

Table 10: Comparison of Italian Registries mean prevalence by macro-areas

Graf 10

Years since diagnosis	Italy	South	Centre	North East	North West	Milan
0-2	28.8	12.5	28.5	31.7	35.7	41.4
2-5	33.1	16.0	32.9	35.6	41.3	49.4
5-10	35.4	14.7	38.5	36.3	45.4	49.0
10-15	20.7	8.5	18.4	26.0	23.4	28.5
15-20	10.1	5.0	8.8	11.2	12.7	14.9
>20	8.3	3.5	8.9	9.1	10.1	12.3

Table 11: 5 years relative survival by macro-areas

Graf 11

Area	Relative survival (95% CI)
Milan	82.4 (78.6‑86.2)
North West	83.6 (81.5‑85.5)
North Est	82.1 (80.3‑83.8)
Centre	81.7 (78.5‑84.5)
South	72.5 (68.0‑76.6)
Italy	81.6 (80.4‑82.8)

Table 12: Relative survival by age since diagnosis

Age class	0	1	2	3	4	5
15-44	100.00	98.30	96.60	93.60	91.20	90.70
45-59	100.00	95.60	90.60	86.70	85.10	82.20
60-74	100.00	90.60	84.10	81.30	79.40	75.60
75+	100.00	97.10	88.70	82.50	79.20	77.90

Table 13: 5 years relative survival by biennium of incidence

Years since diagnosis	1999‑2000	2001‑2002	2003‑2004	2005‑2006
1	94.8	96.1	94	93.3
2	89.1	92.1	87.6	86
3	83.6	89.7	83.7	82.5
4	80.9	86.7	82.9	80.5
5	76.8	83.1	81.7	79.3

Table 14: Rates distribution by deprivation index

‑	1	2	3	4	5
Incidence	23	18.5	15.5	15.6	14.3
Mortality	6.6	2.5	5	3.3	5

Table 15: Relative survival by deprivation index

Years since diagnosis	Most deprived	Most affluent
0	100.0	100.0
1	92.0	92.8
2	80.3	88.1
3	78.3	80.5
4	76.4	77.1
5	76.2	76.0