Skin melanoma - LadiesRates per 100,000 inhabitants
Table 1: Incidence: frequencies, crude and standardized rates per year
Incidence | 1999 | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 1999‑2006 |
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Count | 99 | 110 | 123 | 134 | 87 | 98 | 77 | 111 | 839 |
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Crude rate | 14.6 | 16.3 | 18.3 | 20.0 | 13.1 | 14.5 | 11.2 | 16.1 | 15.5 (14.5‑16.6) |
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Standardized rate | Italy 2001 | 13.0 | 14.7 | 16.9 | 17.7 | 11.4 | 12.4 | 9.6 | 14.0 | 13.7 (12.8‑14.7) |
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Standardized rate | Europe | 11.2 | 12.5 | 15.1 | 15.0 | 9.7 | 10.6 | 7.9 | 11.7 | 11.7 (10.9‑12.6) |
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Standardized rate | World | 8.7 | 10.0 | 12.6 | 11.8 | 7.8 | 8.5 | 6.2 | 9.2 | 9.3 (8.6‑10.1) |
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Table 2: Mortality: frequencies, crude and standardized rates per year
Mortality | 1999 | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 1999‑2006 |
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Count | 17 | 24 | 22 | 19 | 23 | 18 | 20 | 14 | 157 |
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Crude rate | 2.5 | 3.6 | 3.3 | 2.8 | 3.5 | 2.7 | 2.9 | 2.0 | 2.9 (2.5‑3.4) |
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Standardized rate | Italy 2001 | 2.0 | 2.6 | 2.6 | 2.2 | 2.5 | 2.2 | 2.3 | 1.7 | 2.2 (1.9‑2.6) |
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Standardized rate | Europe | 1.5 | 1.7 | 1.9 | 1.6 | 1.7 | 1.7 | 1.7 | 1.3 | 1.6 (1.3‑1.9) |
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Standardized rate | World | 1.1 | 1.1 | 1.4 | 1.1 | 1.2 | 1.3 | 1.2 | 0.9 | 1.1 (0.9‑1.4) |
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Table 3: Register quality indicators per year
Indicator | 1999 | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 1999‑2006 |
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Mortality/Incidence ratio (%) | 15.4 | 17.7 | 15.4 | 12.4 | 21.9 | 17.7 | 24.0 | 12.1 | 16.1 |
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Cito-histologically confirmed (%) | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 |
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Death certificate only - DCO (%) | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
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Table 4: Comparison of Italian Registries mean prevalence by macro-areas
_ | Milan | North West | North East | Centre | South | Italy |
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Incidence | 10.0 | 12.4 | 12.0 | 10.9 | 6.6 | 10.8 |
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Mortality | 1.6 | 1.4 | 1.7 | 1.6 | 1.3 | 1.6 |
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Table 5: Basis of diagnosis per period
_ | 1999‑2002 | % | 2003‑2006 | % | 1999‑2006 | % |
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Histological | 465 | 99.8 | 373 | 100.0 | 838 | 99.9 |
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Citological | 1 | 0.2 | 0 | 0.0 | 1 | 0.1 |
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Clinical | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
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DCO | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
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Table 6: More frequent morphologies
Morphology | N | % |
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Superficial spreading melanoma (C44._) | 166 | 44.5 |
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Epithelioid cell melanoma | 100 | 26.8 |
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Malignant melanoma, NOS (except juvenile melanoma M87700) | 43 | 11.5 |
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Lentigo maligna melanoma (C44._) | 19 | 5.1 |
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Nodular melanoma (C44._) | 15 | 4.0 |
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Mixed epithelioid and spindle cell melanoma | 13 | 3.5 |
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Table 7: Age distribution of rates
Age groups | Incidence | Mortality |
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0 | 0.0 | 0.0 |
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1-4 | 0.0 | 0.0 |
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5-9 | 0.0 | 0.0 |
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10-14 | 0.0 | 0.0 |
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15-19 | 2.4 | 0.0 |
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20-24 | 4.9 | 0.0 |
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25-29 | 5.8 | 0.0 |
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30-34 | 8.8 | 0.0 |
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35-39 | 12.2 | 2.3 |
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40-44 | 18.5 | 2.5 |
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45-49 | 15.2 | 1.2 |
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50-54 | 12.6 | 4.2 |
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55-59 | 18.0 | 2.7 |
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60-64 | 18.8 | 3.1 |
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65-69 | 20.8 | 2.6 |
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70-74 | 20.5 | 3.4 |
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75-79 | 19.9 | 8.0 |
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80-84 | 28.6 | 6.1 |
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85+ | 17.9 | 14.9 |
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Table 8: Temporal trends of rates
Year | Mortality | Incidence |
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1999 | 1.5 | 11.2 |
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2000 | 1.7 | 12.5 |
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2001 | 1.9 | 15.1 |
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2002 | 1.6 | 15.0 |
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2003 | 1.7 | 9.7 |
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2004 | 1.7 | 10.6 |
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2005 | 1.7 | 7.9 |
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2006 | 1.3 | 11.7 |
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Table 10: Comparison of Italian Registries mean prevalence by macro-areas
Years since diagnosis | Italy | South | Centre | North East | North West | Milan |
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0-2 | 28.0 | 13.4 | 26.9 | 32.1 | 31.9 | 32.1 |
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2-5 | 34.1 | 16.5 | 34.0 | 37.5 | 40.8 | 47.8 |
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5-10 | 45.7 | 18.5 | 48.4 | 50.1 | 52.9 | 53.3 |
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10-15 | 29.6 | 11.2 | 25.8 | 36.4 | 36.4 | 35.3 |
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15-20 | 17.5 | 7.3 | 16.2 | 20.7 | 19.8 | 22.5 |
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>20 | 26.0 | 10.1 | 25.1 | 30.1 | 31.1 | 32.1 |
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Table 11: 5 years relative survival by macro-areas
Area | Relative survival (95% CI) |
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Milan | 90.5 (87.4‑93.7) |
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North West | 90.2 (88.4‑91.7) |
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North Est | 88.9 (87.4‑90.3) |
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Centre | 87.6 (85.0‑89.8) |
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South | 82.3 (77.9‑85.9) |
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Italy | 88.6 (87.6‑89.5) |
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Table 12: Relative survival by age since diagnosis
Age class | 0 | 1 | 2 | 3 | 4 | 5 |
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15-44 | 100.00 | 98.80 | 98.00 | 98.00 | 98.00 | 96.90 |
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45-59 | 100.00 | 96.80 | 94.60 | 92.30 | 90.50 | 89.20 |
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60-74 | 100.00 | 98.50 | 93.90 | 92.30 | 89.20 | 89.20 |
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75+ | 100.00 | 91.50 | 86.00 | 84.00 | 81.50 | 75.20 |
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Table 13: 5 years relative survival by biennium of incidence
Years since diagnosis | 1999‑2000 | 2001‑2002 | 2003‑2004 | 2005‑2006 |
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1 | 95.9 | 97.3 | 98.8 | 95.5 |
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2 | 90.2 | 96 | 96 | 93 |
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3 | 88.3 | 94.9 | 95 | 92.1 |
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4 | 86 | 93.7 | 93.7 | 88.5 |
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5 | 84.7 | 92.2 | 92.6 | 87 |
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Table 14: Rates distribution by deprivation index
‑ | 1 | 2 | 3 | 4 | 5 |
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Incidence | 18.7 | 14.7 | 10.9 | 13.1 | 9.2 |
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Mortality | 2.7 | 3.1 | 2.5 | 2.3 | 2.7 |
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Table 15: Relative survival by deprivation index
Years since diagnosis | Most deprived | Most affluent |
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0 | 100.0 | 100.0 |
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1 | 94.5 | 99.2 |
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2 | 88.6 | 95.8 |
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3 | 88.6 | 95.0 |
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4 | 87.3 | 90.9 |
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5 | 83.9 | 89.0 |
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