Mesothelioma - GentsRates per 100,000 inhabitants
Table 1: Incidence: frequencies, crude and standardized rates per year
Incidence | 1999 | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 1999‑2006 |
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Count | 21 | 23 | 23 | 28 | 28 | 31 | 31 | 24 | 209 |
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Crude rate | 3.5 | 3.9 | 3.9 | 4.8 | 4.8 | 5.2 | 5.1 | 3.9 | 4.4 (3.8‑5.0) |
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Standardized rate | Italy 2001 | 3.7 | 4.3 | 3.7 | 4.6 | 4.6 | 4.9 | 5.1 | 4.0 | 4.4 (3.8‑5.0) |
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Standardized rate | Europe | 2.4 | 2.6 | 2.8 | 3.0 | 3.0 | 3.0 | 3.3 | 2.5 | 2.8 (2.4‑3.2) |
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Standardized rate | World | 1.5 | 1.7 | 1.9 | 2.0 | 2.0 | 1.9 | 2.2 | 1.7 | 1.9 (1.6‑2.2) |
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Table 2: Mortality: frequencies, crude and standardized rates per year
Mortality | 1999 | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 1999‑2006 |
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Count | 14 | 30 | 14 | 28 | 27 | 29 | 25 | 20 | 187 |
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Crude rate | 2.3 | 5.1 | 2.4 | 4.8 | 4.6 | 4.9 | 4.1 | 3.2 | 3.9 (3.4‑4.5) |
---|
Standardized rate | Italy 2001 | 2.3 | 5.6 | 2.6 | 4.8 | 4.5 | 4.7 | 4.3 | 3.3 | 4.0 (3.5‑4.7) |
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Standardized rate | Europe | 1.6 | 3.3 | 1.5 | 2.9 | 2.7 | 3.0 | 2.4 | 1.9 | 2.4 (2.1‑2.8) |
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Standardized rate | World | 1.1 | 2.0 | 0.9 | 1.8 | 1.7 | 2.0 | 1.4 | 1.2 | 1.5 (1.3‑1.8) |
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Table 3: Register quality indicators per year
Indicator | 1999 | 2000 | 2001 | 2002 | 2003 | 2004 | 2005 | 2006 | 1999‑2006 |
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Mortality/Incidence ratio (%) | 62.2 | 130.2 | 70.3 | 104.3 | 97.8 | 95.9 | 84.3 | 82.5 | 90.9 |
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Cito-histologically confirmed (%) | 95.2 | 91.3 | 95.7 | 92.9 | 89.3 | 90.3 | 87.1 | 87.5 | 90.9 |
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Death certificate only - DCO (%) | 4.8 | 0.0 | 0.0 | 3.6 | 0.0 | 3.2 | 6.5 | 4.2 | 2.9 |
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Table 4: Comparison of Italian Registries mean prevalence by macro-areas
_ | Milan | North West | North East | Centre | South | Italy |
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Incidence | 2.9 | 3.7 | 3.1 | 1.2 | 1.9 | 2.5 |
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Mortality | 2.5 |
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Table 5: Basis of diagnosis per period
_ | 1999‑2002 | % | 2003‑2006 | % | 1999‑2006 | % |
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Histological | 74 | 77.9 | 91 | 79.8 | 165 | 78.9 |
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Citological | 15 | 15.8 | 10 | 8.8 | 25 | 12.0 |
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Clinical | 4 | 4.2 | 9 | 7.9 | 13 | 6.2 |
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DCO | 2 | 2.1 | 4 | 3.5 | 6 | 2.9 |
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Table 6: More frequent morphologies
Morphology | N | % |
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Epithelioid mesothelioma, malignant | 52 | 51.5 |
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Mesothelioma, malignant | 34 | 33.7 |
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Mesothelioma, biphasic, malignant | 12 | 11.9 |
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Fibrous mesothelioma, malignant | 3 | 3.0 |
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Table 7: Age distribution of rates
Age groups | Incidence | Mortality |
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0 | 0.0 | 0.0 |
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1-4 | 0.0 | 0.0 |
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5-9 | 0.0 | 0.0 |
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10-14 | 0.0 | 0.0 |
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15-19 | 0.0 | 0.0 |
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20-24 | 0.0 | 0.0 |
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25-29 | 0.0 | 0.0 |
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30-34 | 0.0 | 0.0 |
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35-39 | 0.9 | 0.4 |
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40-44 | 0.5 | 0.0 |
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45-49 | 0.6 | 1.8 |
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50-54 | 0.7 | 1.4 |
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55-59 | 3.8 | 1.3 |
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60-64 | 10.2 | 5.1 |
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65-69 | 10.6 | 9.3 |
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70-74 | 22.0 | 14.1 |
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75-79 | 22.5 | 24.6 |
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80-84 | 22.2 | 35.9 |
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85+ | 26.4 | 26.4 |
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Table 8: Temporal trends of rates
Year | Mortality | Incidence |
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1999 | 1.6 | 2.4 |
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2000 | 3.3 | 2.6 |
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2001 | 1.5 | 2.8 |
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2002 | 2.9 | 3.0 |
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2003 | 2.7 | 3.0 |
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2004 | 3.0 | 3.0 |
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2005 | 2.4 | 3.3 |
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2006 | 1.9 | 2.5 |
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Table 10: Comparison of Italian Registries mean prevalence by macro-areas
Years since diagnosis | Italy | South | Centre | North East | North West | Milan |
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0-2 | 3.4 | 2.3 | 2.1 | 3.7 | 4.6 | 4.7 |
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2-5 | 1.0 | 0.9 | 0.5 | 1.1 | 1.0 | 1.5 |
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5-10 | 0.4 | 0.3 | 0.5 | 0.2 | 0.7 | 0.9 |
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10-15 | 0.2 | 0.0 | 0.0 | 0.6 | 0.2 | 0.2 |
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15-20 | 0.2 | 0.1 | 0.0 | 0.0 | 0.3 | 0.1 |
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>20 | 0.0 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 |
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Table 11: 5 years relative survival by macro-areas
Area | Relative survival (95% CI) |
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Milan | 13.3 (4.3‑22.2) |
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North West | 7.0 (5.1‑9.2) |
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North Est | 7.1 (5.1‑9.5) |
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Centre | 7.8 (3.7‑13.7) |
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South | 14.8 (9.2‑21.7) |
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Italy | 7.7 (6.4‑9.2) |
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Table 12: Relative survival by age since diagnosis
Age class | 0 | 1 | 2 | 3 | 4 | 5 |
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15-44 | 100.00 | 62.40 | 34.80 | 31.40 | 26.40 | 21.30 |
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45-59 | 100.00 | 50.20 | 30.30 | 16.50 | 12.60 | 10.90 |
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60-74 | 100.00 | 36.40 | 16.40 | 11.80 | 10.50 | 9.60 |
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Table 13: 5 years relative survival by biennium of incidence
Years since diagnosis | 1999‑2000 | 2001‑2002 | 2003‑2004 | 2005‑2006 |
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1 | 44.2 | 49.5 | 41.9 | 53.7 |
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2 | 27.2 | 27.4 | 20.7 | 30.8 |
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3 | 24.8 | 15 | 11.4 | 18.8 |
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4 | 23.1 | 8.7 | 11.4 | 14.5 |
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5 | 19 | 6.6 | 11.4 | 12.5 |
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Table 14: Rates distribution by deprivation index
‑ | 1 | 2 | 3 | 4 | 5 |
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Incidence | 1.8 | 2.4 | 2.3 | 2.3 | 2.4 |
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Mortality | 2.8 | 4.3 | 3.6 | 4.1 | 3.6 |
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Table 15: Relative survival by deprivation index
Years since diagnosis | Most deprived | Most affluent |
---|
0 | 100.0 | 100.0 |
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1 | 47.2 | 41.7 |
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2 | 25.7 | 19.7 |
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3 | 16.2 | 10.0 |
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4 | 16.2 | 0.0 |
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5 | 12.4 | 0.0 |
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