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Pancreas - Gents

Rates per 100,000 inhabitants

Table 1: Incidence: frequencies, crude and standardized rates per year

Incidence		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		107	114	121	141	121	136	146	96	982
Crude rate		17.9	19.2	20.5	24.1	20.8	22.8	23.8	15.5	20.6 (19.3‑21.9)
Standardized rate	Italy 2001	18.5	19.7	20.5	23.1	20.0	22.1	24.3	15.9	20.4 (19.2‑21.8)
Standardized rate	Europe	12.4	13.2	13.9	15.6	13.4	14.5	15.7	10.7	13.6 (12.8‑14.5)
Standardized rate	World	8.3	8.7	9.5	10.7	9.0	9.8	10.3	7.2	9.2 (8.5‑9.8)

Table 2: Mortality: frequencies, crude and standardized rates per year

Mortality		1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Count		102	103	109	102	105	106	128	103	858
Crude rate		17.1	17.4	18.5	17.4	18.1	17.8	20.9	16.6	18.0 (16.8‑19.2)
Standardized rate	Italy 2001	18.2	17.3	18.4	17.2	17.3	17.2	21.0	17.1	17.9 (16.7‑19.2)
Standardized rate	Europe	11.8	11.8	12.4	11.1	11.5	11.1	13.6	11.1	11.8 (11.0‑12.6)
Standardized rate	World	7.9	7.8	8.5	7.3	7.7	7.4	9.0	7.3	7.8 (7.3‑8.4)

Table 3: Register quality indicators per year

Indicator	1999	2000	2001	2002	2003	2004	2005	2006	1999‑2006
Mortality/Incidence ratio (%)	98.4	87.8	89.8	74.5	86.5	77.8	86.4	107.5	87.7
Cito-histologically confirmed (%)	55.1	50.9	53.7	61.7	58.7	58.1	51.4	59.4	56.1
Death certificate only - DCO (%)	4.7	3.5	1.7	1.4	0.8	3.7	4.1	2.1	2.8

Table 4: Comparison of Italian Registries mean prevalence by macro-areas

Graf 04

_	Milan	North West	North East	Centre	South	Italy
Incidence	13.5	12.7	14.4	11.5	9.7	12.7
Mortality	11.8	12.1	13.3	10.6	9.4	12.0

Table 5: Basis of diagnosis per period

_	1999‑2002	%	2003‑2006	%	1999‑2006	%
Histological	236	48.9	241	48.3	477	48.6
Citological	33	6.8	41	8.2	74	7.5
Clinical	201	41.6	203	40.7	404	41.1
DCO	13	2.7	14	2.8	27	2.8

Table 6: More frequent morphologies

Morphology	N	%
Adenocarcinoma, NOS	182	64.5
Infiltrating duct carcinoma, NOS (C50._)	41	14.5
Carcinoma, NOS	17	6.0
Neuroendocrine carcinoma, NOS	14	5.0
Mucinous adenocarcinoma	6	2.1
Tumour cells, malignant	6	2.1

Table 7: Age distribution of rates

Graf 07

Age groups	Incidence	Mortality
0	0.0	0.0
1-4	0.0	0.0
5-9	0.0	0.0
10-14	0.0	0.0
15-19	0.0	0.0
20-24	0.0	0.0
25-29	0.6	0.6
30-34	0.4	0.4
35-39	2.2	1.3
40-44	3.0	1.5
45-49	11.0	7.9
50-54	9.5	6.8
55-59	24.5	20.1
60-64	39.6	37.0
65-69	52.3	47.0
70-74	61.3	57.3
75-79	87.7	84.5
80-84	117.8	100.8
85+	131.9	114.3

Table 8: Temporal trends of rates

Graf 08

Year	Mortality	Incidence
1999	11.8	12.4
2000	11.8	13.2
2001	12.4	13.9
2002	11.1	15.6
2003	11.5	13.4
2004	11.1	14.5
2005	13.6	15.7
2006	11.1	10.7

Table 10: Comparison of Italian Registries mean prevalence by macro-areas

Graf 10

Years since diagnosis	Italy	South	Centre	North East	North West	Milan
0-2	10.9	7.5	9.8	11.5	13.0	14.1
2-5	3.4	2.2	2.9	3.9	3.6	4.4
5-10	1.9	1.7	2.4	1.3	2.8	2.7
10-15	1.4	0.7	0.8	2.0	1.5	0.8
15-20	0.4	0.1	0.3	0.4	0.4	0.4
>20	0.2	0.2	0.2	0.2	0.3	0.3

Table 11: 5 years relative survival by macro-areas

Graf 11

Area	Relative survival (95% CI)
Milan	7.0 (4.6‑9.4)
North West	6.8 (5.6‑8.2)
North Est	5.5 (4.6‑6.5)
Centre	5.6 (4.0‑7.6)
South	6.3 (4.6‑8.3)
Italy	6.1 (5.4‑6.7)

Table 12: Relative survival by age since diagnosis

Age class	0	1	2	3	4	5
15-44	100.00	38.50	30.80	30.80	26.50	26.50
45-59	100.00	40.20	21.00	15.30	12.40	11.10
60-74	100.00	29.10	12.60	7.20	6.20	5.20
75+	100.00	15.50	8.60	6.90	5.10	5.10

Table 13: 5 years relative survival by biennium of incidence

Years since diagnosis	1999‑2000	2001‑2002	2003‑2004	2005‑2006
1	24	24.4	28.2	29
2	8.7	11.5	15.8	16
3	6.7	7.1	9	13.1
4	6.3	5	7	11.6
5	6.3	4.6	7	9.3

Table 14: Rates distribution by deprivation index

‑	1	2	3	4	5
Incidence	17.8	18.6	18.7	19.6	22.9
Mortality	16.8	17.5	15.5	17.4	18.9

Table 15: Relative survival by deprivation index

Years since diagnosis	Most deprived	Most affluent
0	100.0	100.0
1	25.4	28.2
2	14.4	16.7
3	12.9	13.7
4	10.5	13.7
5	9.5	13.3